CuRE Cyto

Automate cytogenetics data entry

Eliminate manual entry of cytogenetics data with a parser that understands ISCN 2016 and 2020 specifications — including traditional karyotypes, FISH results, and complex nomenclature.

Parse ISCN strings into structured data

The CuRE Cyto parser understands the full complexity of cytogenetic nomenclature. It extracts chromosome counts, sex, abnormality types, breakpoints, and cell counts — turning free-text ISCN strings into structured, queryable data.

  • Karyotype analysis: Parse standard and complex karyotype strings including numerical and structural abnormalities
  • FISH results: Recognize and structure fluorescence in situ hybridization results with probe details
  • Validation: Identify valid and invalid nomenclature, flagging issues for review
  • Structured output: JSON output ready for integration into registries, databases, or analytic pipelines

Example: Karyotype parsing

ISCN string 46,XX,+21,t(4;14)(p12;q11)[5] parsed into a tree showing chromosomes, sex, abnormalities, and cell count

Interactive Demo

Try the ISCN Parser

Paste a cytogenetic string and see it parsed into structured data — right in your browser.

Try:

Enter an ISCN string above or click an example to see it parsed.

This is a lightweight demo — for full ISCN 2016/2020 parsing, visit cyto.principia.health

Multiple ways to use

Whether you need one-off parsing or full integration, CuRE Cyto adapts to your workflow.

Web Client

Parse strings individually via the web interface and get structured JSON output instantly.

API Integration

Incorporate parsing into your registries or data systems via API for automated, scalable processing.

Parsing as a Service

Send us your ISCN strings or reports and we'll process them for you — ideal for batch processing.

Interested in CuRE Cyto?

Whether you need to automate cytogenetics data entry for a registry or integrate parsing into your data pipeline, we can help.